MOOC: Validation of liquid chromatography mass spectrometry (LC-MS) methods (analytical chemistry) course

Self test 2.4

1.

What makes MS detector in LC-MS a more useful tool for analyte identity confirmation than UV-Vis photodiode array detector?

2.

Mass spectra of compounds obtained with the common LC-MS ion sources are usually more characteristic than UV-Vis spectra

3.

MS detector enables higher quantitative accuracy than UV-Vis detector

4.

MS detector has MSn possibilities

5.

MS detector’s ability of analyte identification is less influenced by peak overlap

6.

LC separation of isomeric forms of A and B was not successful and MS/MS spectra of A and B were identical. Can HRMS help to achieve selectivity between A and B?

 


 

Previous
Next