3.
The analyst is evaluating robustness with full factorial design. Most of all she is concerned about limit of detection. From previous knowledge she knows that LoD in case of her method is mostly influenced by ionization source parameters. Therefore she determined LoD dependence on nebulizer gas pressure and drying gas temperature (data given below).
|
Factor A
Nebulizer gas pressure (psi)
|
Factor B
Drying gas temp. (°C)
|
LoD (µg/L)
|
|
55
|
360
|
3.2
|
|
55
|
340
|
3.8
|
|
45
|
360
|
2.8
|
|
45
|
340
|
3.7
|
Calculate how large is the effect of the nebulizer gas pressure|on the drying gas temperature and on the interaction of drying gas temperature* nebulizer gas pressure on the LoD!
Please use dots (.) instead of commas (|) for separating the decimals and present the answer with 2 decimals.
The effect of the factor A (nebulizer gas pressure) on LOD is µg/L.
The effect of the factor B (drying gas temperature) on LOD is µg/L.
The effect of the interaction of factors A and B (drying gas temperature*nebulizer gas pressure) on LOD is µg/L.
Create an order of significants of effects and interactions from most impactful (top) to least impactful (bottom).
1. (most impactful)
2.
3. (least impactful)
