Validation of liquid chromatography mass spectrometry (LC-MS) methods
- Course introduction
- 1. Validation: General
- 2. Selectivity and identity confirmation
- 2.1. Selectivity: LC selectivity
- Self test 2.1
- 2.2. Selectivity: detector-side (MS) selectivity
- Self test 2.2
- 2.3. Selectivity examples
- 2.4. Introduction to identity confirmation
- Self test 2.4
- 2.5. Identity confirmation: retention time
- 2.6. Identity confirmation by MS
- 2.7. Identity confirmation examples
- Self test 2.7
- 3. Linearity of signal, linear range, sensitivity
- 4. Precision
- 5. Trueness
- 6. Precision and trueness: some additional aspects
- 7. Accuracy
- 8. Stability
- 9. LoD and LoQ
- 10. Ruggedness, robustness
- Acknowledgements
- Frequently asked questions
- References
- Glossary
- What our participants say?