Validation of liquid chromatography mass spectrometry (LC-MS) methods

Glossary

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Scedasticity

The distribution of error terms.

Selectivity

The extent to which other substances interfere with the determination of a substance according to a given procedure.

Sensitivity

The change in instrument response, which corresponds to a change in the measured quantity; the gradient of the response curve.

Stability

Stability (ST%) characterizes the change in the analyte content in the given matrix under the specific conditions and over the period of time.

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