Validation of liquid chromatography mass spectrometry (LC-MS) methods

Glossary

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Precision

Characterizes the closeness of agreement between the measured values obtained by replicate measurements on the same or similar objects under specified conditions.

Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug (e.g. by ester bond cleavage within prodrug). Inactive prodrugs are pharmacologically inactive medications that are metabolized into an active form within the body.