Validation of liquid chromatography mass spectrometry (LC-MS) methods
Glossary
Measurement uncertainty
Measurement uncertainty (or simply uncertainty) defines an interval around the measured value CMEASURED, where the true value CTRUE lies with some predefined probability. The measurement uncertainty U itself is the half-width of that interval and is always non-negative. This definition differs from the VIM [ref 6] definition (but does not contradict it) and we use it here as it is generally easier to understand and to relate to practice.