CEMCE publications 2020

TK143 Publications 2020

• Götte, B., Utt, A., Fragkoudis, R., Merits, A., McInerney, G. (2020) Sensitivity of alphaviruses to G3BP deletion correlates with efficiency of replicase polyprotein processing” Journal of Virology, pii: JVI.01681-19. doi: 10.1128/JVI.01681-19.
• Lello, L.S., Utt, A., Bartholomeeusen, K., Wang, S., Rausalu, K., Kendall, C., Coppens, S., Fragkoudis, R., Tuplin, A., Alphey, L., Ariën, K.K. and Merits, A. (2020). Cross-utilisation of template RNAs by alphavirus replicases. Plos Pathogens 16(9):e1008825. doi: 10.1371/journal.ppat.1008825.
• Law, Y.-S., Wang, S., Tan, Y.B., Shih, O., Utt, A., Goh, W.Y., Lian, B.-J., Chen, M.W., Jeng, U-S., Merits, A. and Luo, D (2020). Inter-domain flexibility of chikungunya virus nsP2 helicase-protease differently influences viral RNA replication and infectivity. Journal of Virology, doi: 10.1128/JVI.01470-20
• Bryden, S.R., Pingen, M., Lefteri, D.A., Major, J., Delang, L., Jacobs, S., Abdelnabi, R., Neyts, J., Miltenburg, J., Khalid, H., Tuplin, A., Merits, A., Pondeville, E., Edgar, J., Graham, G.J., Shams, K. and McKimmie, C.S. (2020). Pan-viral protection against arboviruses by targeting inoculation site-based skin macrophages. Science Translational Medicine, 12, pii: eaax2421. doi: 10.1126/scitranslmed.aax2421
• Liu, X., Mutso, M., Cherkashchenko, L., Zusinaite, E., Herrero, L.J., Doggett, S.L., Haniotis, J., Merits, A., Herring, B.L., Taylor, A. and Mahalingam, S. (2020). Identification of natural molecular determinants of Ross River virus type I IFN modulation. Journal of Virology. pii: JVI.01788-19. doi: 10.1128/JVI.01788-19
• Bakhache, W., Neyret, A., Bernard, E., Merits, A. and Briant, L (2020). Palmitoylated cysteines in Chikungunya virus nsP1 are critical for targeting to cholesterol-rich plasma membrane microdomains with functional consequences for viral genome replication. Journal of Virolology, JVI.02183-19. doi: 10.1128/JVI.02183-19
• Mutso M., St John, J.A., Ling, Z.L., Burt, F.J., Poo, Y.S., Liu, X., Žusinaite, E., Grau, G.E., Hueston, L., Merits, A., King, N.J.C., Ekberg, J.A.K. and Mahalingam, S. (2020) Basic insights into Zika virus infection of neuroglial and brain endothelial cells. Journal of General Virology. doi: 10.1099/jgv.0.001416.
• Shimizu, J.F., Martins, D.O.S., McPhillie, M.J., Roberts, G.C., Zothner, C., Merits A., Harris M. and Jardim, A.C.G. (2020) Is the ADP ribose site of the Chikungunya virus NSP3 Macro domain a target for antiviral approaches? Acta Trop., 207, doi: 10.1016/j.actatropica.2020.105490.
• Kaur, P., Lello, L.S., Utt, A., Dutta, S.K., Merits, A., and Chu, J.J.H. (2020). Bortezomib inhibits Chikungunya virus replication by interfering with viral protein synthesis. PloS Neglected Tropical Diseases, 14(5):e0008336. doi: 10.1371/journal.pntd.0008336
• Royle, J., Ramírez-Santana, C., Akpunarlieva, S., Donald, C.L., Gestuveo, R.J., Anaya, J-M., Merits, A., Burchmore, R., Kohl, A. and Varjak, M. (2020) Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection. Viruses 2020, 12, 524; https://doi.org/10.3390/v12050524
• Wang, T., Merits, A., Wu, Y., Wang, M., Jia, R., Zhu, D., Liu, M., Zhao, X., Yang, Q., Wu, Y., Zhang, S., Liu, Y., Zhang, L., Yu, Y., Pan, L., Chen, S. and Cheng, A. (2020). Cis-acting sequences and secondary structures in untranslated regions of duck tembusu virus RNA are important for cap-independent translation and viral proliferation. Journal of Virology, doi: 10.1128/JVI.00906-20
• Tng, P.Y.L., Paladino, L.C., Verkuijl, S.A.N., Purcell, J., Merits, A., Leftwich, P.T., Fragkoudis, R, Noad, R. and Luke Alphey, L. (2020) Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression. Communications Biolology 3:413, doi: 10.1038/s42003-020-01142-6.
• Wu, Z., Wu, Y., Zhang, W., Merits, A., Simmonds, P., Wang, M., Jia, R., Zhu, D., Liu, M., Zhao, X., Yang, Q., Wu, Y., Zhang, S., Huang, J., Ou, X., Mao, S., Liu, Y., Zhang, L., Yu, Y., Tian, B., Pan, L., Rehman, M.U., Chen, S. and Cheng, A. (2020). The first nonmammalian pegivirus demonstrates efficient in vitro replication and high lymphotropism. Journal of Virology, doi: 10.1128/JVI.01150-20.
• Gwon, Y.-D., Zusinaite, E., Merits, A., Överby, A.K. and Evander, M. (2020) N-glycosylation in the Pre-Membrane Protein Is Essential for the Zika Virus Life Cycle. Viruses, 12(9):E925, doi: 10.3390/v12090925.
• de Oliveira, D.M., de Andrade Santos, I., Martins, D.O.S., Gonçalves, Y.G., Cardoso-Sousa, L., Sabino-Silva, R., Von Poelhsitz, G., de Faria Franca, R., Nicolau, N. Jr., Pacca, C.C., Merits, A., Harris, M., and Jardim, A.C.G. (2020). Organometallic complex strongly impairs CHIKV entry to the host cells. Frontiers in Microbiology, in press
• 13. Ianevski, A., Yao, R., Fenstad, M.H., Biza, S., Zusinaite, E.,Reisberg, T., Lysvand, H., Løseth, K., Landsem, V.M., Malmring, J.F., Oksenych, V., Erlandsen, S.E., Aas, P.A., Hagen, L., Pettersen, C.H., Tenson, T., Afset, J.E., Nordbø, S.A., Bjørås, M. and Kainov, D.E. (2020) Potential Antiviral Options against SARS-CoV-2 Infection. Viruses, 12(6):642, doi: 10.3390/v12060642.
• 14. Ianevski, A., Kulesskiy, E., Krpina, K., Lou, G., Aman, Y., Bugai, A., Aasumets, K., Akimov, Y., Bulanova, D., Gildemann, K., Arutyunyan, A.F., Susova, O.Y., Zhuze, A.L., Ji, P., Wang, W., Holien, T., Bugge, M., Zusinaite, E., Oksenych, V., Lysvand, H., Gerhold, J.M., Bjørås, M., Johansen, P., Waage, A., Heckman, C.A., Fang, E.F. and Kainov, E.D. (2020) Chemical, Physical and Biological Triggers of Evolutionary Conserved Bcl-xL-Mediated Apoptosis, Cancers, 12(6):1694, doi: 10.3390/cancers12061694.
• 15. Ianevski, A., Yao, R., Biza, S., Zusinaite, E., Mannik, A., Kivi, G., Planken, A., Kurg, K., Tombak, E.-M., Ustav, M.Jr., Shtaida, N., Kulesskiy, E., Jo, E., Yang, J., Lysvand, H., Løseth, K., Oksenych, V., Aas, P.A., Tenson, T., Vitkauskienė, A. , Windisch, M.P., Fenstad, M.H., Nordbø, S.A., Ustav, M., Bjørås, M. and Kainov, D.E. (2020) Identification and Tracking of Antiviral Drug Combinations. Viruses. 12(10):1178. doi: 10.3390/v12101178.
• Piirsoo A, Kala M, Sankovski E, Ustav M, Piirsoo M. Uncovering the Role of the E1 Protein in Different Stages of Human Papillomavirus 18 Genome Replication. J Virol. 2020 Sep 29;94(20):e00674-20. doi: 10.1128/JVI.00674-20. Print 2020 Sep 29.
• Adam L, Tchitchek N, Todorova B, Rosenbaum P, Joly C, Poux C, Chapon C, Spetz AL, Ustav M, Le Grand R, Martinon F. Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination. J Immunol. 2020 Jun 15;204(12):3375-3388. doi: 10.4049/jimmunol.1900517. Epub 2020 May 8. PMID: 32385135 Free PMC article.
• Zhang L, Takahashi Y, Hsu P-K, Kollist H, Merilo E, Krysan PJ, Schroeder JI. 2020. FRET kinase sensor development reveals SnRK2/OST1 activation by ABA but not by MeJA and high CO2 during stomatal closure. eLife DOI: 10.7554/eLife.56351
• Chan C, Panzeri D, Okuma E, Toldsepp K, Wang Y-Y, Guan-Yu L, Chin T-C, Yeh Yu-Hung, Yeh H-L, Yekondi S, Huang Y-H, Huang T-Y, Chiou T-J, Murata Y, Kollist, H, Zimmerli L. (2020) STRESS INDUCED FACTOR 2 Regulates Arabidopsis Stomatal Immunity through Phosphorylation of the Anion Channel SLAC1 Plant Cell, 32: 2216-2236
• Schulze S, Dubeaux G, Ceciliato PHO, Munemasa S, Nuhkat M, Yarmolinsky D, Aguilar J, Diaz R, Azoulay-Shemer T, Steinhorst L, Offenborn JN, Kudla J, Kollist, H, Schroeder J. (2020) A role for calcium-dependent protein kinases in differential CO2- and ABA-controlled stomatal closing and low CO2-induced stomatal opening in Arabidopsis. NEW PHYTOLOGIST, DOI: 10.1111/nph.17079.
• Kalliola M, Jakobson L, Davidsson P, Pennanen V, Waszczak C, Yarmolinsky D, Zamora, Palva ET, Kariola T, Kollist H, Brosche M. (2020) Differential role of MAX2 and strigolactones in pathogen, ozone, and stomatal responses. Plant Direct. 2020;4:1–14. https://doi.org/10.1002/pld3.206
• Jiang Y, Ye J, Rasulov B, Niinemets Ü. 2020. Role of Stomatal Conductance in Modifying the Dose Response of Stress-Volatile Emissions in Methyl Jasmonate Treated Leaves of Cucumber (Cucumis Sativa). International J of Molecular Sciences, 21. https://www.mdpi.com/1422-0067/21/3/1018
• Johansson KSL, El-Soda M, Pagel E, Meyer RC, Toldsepp K, Nilsson A, Brosche M, Kollist H, Uddling J, Andersson MX. (2020) Genetic controls of short- and long-term stomatal CO2 responses in Arabidopsis thaliana. Annals of Botany 126: 179-190.
• Crowe-McAuliffe C, Takada H, Murina V, Polte C, Kasvandik S, Tenson T, Ignatova Z, Atkinson GC, Wilson DN, Hauryliuk V. (2020). Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP. Mol Cell. 2020 Nov 19:S1097-2765(20)30780-2. doi: 10.1016/j.molcel.2020.11.002.
• Lanno GM, Ramos C, Preem L, Putrinš M, Laidmäe I, Tenson T, Kogermann K. (2020). Antibacterial Porous Electrospun Fibers as Skin Scaffolds for Wound Healing Applications. ACS Omega. 2020 Nov 12;5(46):30011-30022. doi: 10.1021/acsomega.0c04402.
• Kaldalu N, Hauryliuk V, Turnbull KJ, La Mensa A, Putrinš M, Tenson T. (2020). In Vitro Studies of Persister Cells. Microbiol Mol Biol Rev. 2020 Nov 11;84(4):e00070-20. doi: 10.1128/MMBR.00070-20.
• Kõiv V, Adamberg K, Adamberg S, Sumeri I, Kasvandik S, Kisand V, Maiväli Ü, Tenson T. (2020). Microbiome of root vegetables-a source of gluten-degrading bacteria.Appl Microbiol Biotechnol. 2020 Oct;104(20):8871-8885. doi: 10.1007/s00253-020-10852-0.
• Telling K, Brauer A, Laht M, Kalmus P, Toompere K, Kisand V, Maimets M, Remm M, Tenson T, Lutsar I. (2020). Characteristics of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae and Contact to Animals in Estonia. Microorganisms. 2020 Jul 27;8(8):1130. doi: 10.3390/microorganisms8081130.
• Jimmy S, Saha CK, Kurata T, Stavropoulos C, Oliveira SRA, Koh A, Cepauskas A, Takada H, Rejman D, Tenson T, Strahl H, Garcia-Pino A, Hauryliuk V, Atkinson GC. (2020). A widespread toxin-antitoxin system exploiting growth control via alarmone signaling. Proc Natl Acad Sci U S A. 2020 May 12;117(19):10500-10510. doi: 10.1073/pnas.1916617117.
• Jõers A, Liske E, Tenson T. (2020). Dividing subpopulation of Escherichia coli in stationary phase. Res Microbiol. 2020 Apr-Jun;171(3-4):153-157. doi: 10.1016/j.resmic.2020.02.002.
• Takada H, Roghanian M, Caballero-Montes J, Van Nerom K, Jimmy S, Kudrin P, Trebini F, Murayama R, Akanuma G, Garcia-Pino A, Hauryliuk V. (2020). Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p)ppGpp synthesis. Nucleic Acids Res. 2020 Dec 16:gkaa1187. doi: 10.1093/nar/gkaa1187.
• Wilson DN, Hauryliuk V, Atkinson GC, O’Neill AJ. (2020). Target protection as a key antibiotic resistance mechanism. Nat Rev Microbiol. 2020 Nov;18(11):637-648. doi: 10.1038/s41579-020-0386-z.
• Takada H, Roghanian M, Murina V, Dzhygyr I, Murayama R, Akanuma G, Atkinson GC, Garcia-Pino A, Hauryliuk V. (2020). The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of ‘Long’ RelA-SpoT Homolog Enzymes by Ribosomal Complexes. Front Microbiol. 2020 Feb 28;11:277. doi: 10.3389/fmicb.2020.00277.
• Peyrusson F, Varet H, Nguyen TK, Legendre R, Sismeiro O, Coppée JY, Wolz C, Tenson T, Van Bambeke F. (2020). Intracellular Staphylococcus aureus persisters upon antibiotic exposure.Nat Commun. 2020 May 4;11(1):2200. doi: 10.1038/s41467-020-15966-7.
• Andersen PI, Ianevski A, Lysvand H, Vitkauskiene A, Oksenych V, Bjørås M, Telling K, Lutsar I, Dumpis U, Irie Y, Tenson T, Kantele A, Kainov DE. (2020). Discovery and development of safe-in-man broad-spectrum antiviral agents. Int J Infect Dis. 2020 Apr;93:268-276. doi: 10.1016/j.ijid.2020.02.018.
• Irie Y, La Mensa A, Murina V, Hauryliuk V, Tenson T, Shingler V. (2020). Hfq-Assisted RsmA Regulation Is Central to Pseudomonas aeruginosa Biofilm Polysaccharide PEL Expression. Front Microbiol. 2020 Nov 17;11:482585. doi: 10.3389/fmicb.2020.482585.
• Prommik P, Kolk H, Maiväli Ü, Pääsuke M, Märtson A. (2020). High variability in hip fracture post-acute care and dementia patients having worse chances of receiving rehabilitation: an analysis of population-based data from Estonia. Eur Geriatr Med. 2020 Aug;11(4):581-601. doi: 10.1007/s41999-020-00348-5.
• Noreikiene K, Ozerov M, Ahmad F, Kõiv T, Kahar S, Gross R, Sepp M, Pellizzone A, Vesterinen EJ, Kisand V, Vasemägi A. (2020). Humic-acid-driven escape from eye parasites revealed by RNA-seq and target-specific metabarcoding. Parasit Vectors. 2020 Aug 28;13(1):433. doi: 10.1186/s13071-020-04306-9.
• Kivistik C, Knobloch J, Käiro K, Tammert H, Kisand V, Hildebrandt JP, Herlemann DPR. (2020). Impact of Salinity on the Gastrointestinal Bacterial Community of Theodoxus fluviatilis.Front Microbiol. 2020 May 8;11:683. doi: 10.3389/fmicb.2020.00683.
• Kirs M, Kisand V, Nelson CE, Dudoit T, Moravcik PS. (2020). Distinct bacterial communities in tropical island aquifers. PLoS One. 2020 Apr 30;15(4):e0232265. doi: 10.1371/journal.pone.0232265.
• Campbell K, Westholm J, Kasvandik S, Di Bartolomeo F, Mormino M, Nielsen J. (2020). Building blocks are synthesized on demand during the yeast cell cycle. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7575-7583. doi: 10.1073/pnas.1919535117.
• Marano RBM, Fernandes T, Manaia CM, Nunes O, Morrison D, Berendonk TU, Kreuzinger N, Tenson T, Corno G, Fatta-Kassinos D, Merlin C, Topp E, Jurkevitch E, Henn L, Scott A, Heß S, Slipko K, Laht M, Kisand V, Di Cesare A, Karaolia P, Michael SG, Petre AL, Rosal R, Pruden A, Riquelme V, Agüera A, Esteban B, Luczkiewicz A, Kalinowska A, Leonard A, Gaze WH, Adegoke AA, Stenstrom TA, Pollice A, Salerno C, Schwermer CU, Krzeminski P, Guilloteau H, Donner E, Drigo B, Libralato G, Guida M, Bürgmann H, Beck K, Garelick H, Tacão M, Henriques I, Martínez-Alcalá I, Guillén-Navarro JM, Popowska M, Piotrowska M, Quintela-Baluja M, Bunce JT, Polo-López MI, Nahim-Granados S, Pons MN, Milakovic M, Udikovic-Kolic N, Ory J, Ousmane T, Caballero P, Oliver A, Rodriguez-Mozaz S, Balcazar JL, Jäger T, Schwartz T, Yang Y, Zou S, Lee Y, Yoon Y, Herzog B, Mayrhofer H, Prakash O, Nimonkar Y, Heath E, Baraniak A, Abreu-Silva J, Choudhury M, Munoz LP, Krizanovic S, Brunetti G, Maile-Moskowitz A, Brown C, Cytryn E. (2020). A global multinational survey of cefotaxime-resistant coliforms in urban wastewater treatment plants. Environ Int. 2020 Nov;144:106035. doi: 10.1016/j.envint.2020.106035.
• Rooda I, Hensen K, Kaselt B, Kasvandik S, Pook M, Kurg A, Salumets A, Velthut-Meikas A. (2020). Target prediction and validation of microRNAs expressed from FSHR and aromatase genes in human ovarian granulosa cells. Sci Rep. 2020 Feb 10;10(1):2300. doi: 10.1038/s41598-020-59186-x.
• Faustova I, Bulatovic L, Matiyevskaya F, Valk E, Örd M, Loog M.A new linear cyclin docking motif that mediates exclusively S-phase CDK-specific signaling. EMBO J. 2020 Nov 19:e105839. doi: 10.15252/embj.2020105839. Online ahead of print. PMID: 33210757
• Örd M, Faustova I, Loog M.The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV. Sci Rep. 2020 Oct 9;10(1):16944. doi: 10.1038/s41598-020-74101-0.PMID: 33037310 Free PMC article.
• Bandyopadhyay S, Bhaduri S, Örd M, Davey NE, Loog M, Pryciak PM. Comprehensive Analysis of G1 Cyclin Docking Motif Sequences that Control CDK Regulatory Potency In Vivo. Curr Biol. 2020 Nov 16;30(22):4454-4466.e5. doi: 10.1016/j.cub.2020.08.099. Epub 2020 Sep 24. PMID: 32976810
• Valk E, Maljavin A, Loog M. Detection of Multisite Phosphorylation of Intrinsically Disordered Proteins Using Quantitative Mass-Spectrometry. Methods Mol Biol. 2020;2141:819-833. doi: 10.1007/978-1-0716-0524-0_42. PMID: 32696391
• Örd M, Loog M. Detection of Multisite Phosphorylation of Intrinsically Disordered Proteins Using Phos-tag SDS-PAGE. Methods Mol Biol. 2020;2141:779-792. doi: 10.1007/978-1-0716-0524-0_40. PMID: 32696389
• Örd M, Puss KK, Kivi R, Möll K, Ojala T, Borovko I, Faustova I, Venta R, Valk E, Kõivomägi M, Loog M. Proline-Rich Motifs Control G2-CDK Target Phosphorylation and Priming an Anchoring Protein for Polo Kinase Localization. Cell Rep. 2020 Jun 16;31(11):107757. doi: 10.1016/j.celrep.2020.107757. PMID: 32553169 Free PMC article.
• Venta R, Valk E, Örd M, Košik O, Pääbo K, Maljavin A, Kivi R, Faustova I, Shtaida N, Lepiku M, Möll K, Doncic A, Kõivomägi M, Loog M. A processive phosphorylation circuit with multiple kinase inputs and mutually diversional routes controls G1/S decision. Nat Commun. 2020 Apr 15;11(1):1836. doi: 10.1038/s41467-020-15685-z. PMID: 32296067 Free PMC article.
• Viisanen, H.; Nuotio, U.; Kambur, O.; Mahato, A.K.; Jokinen, V.; Lilius, T.; Li, W.; Santos, H.A.; Karelson, M.; Rauhala, P.; Kalso, E.; Sidorova, Y.A. (2020). Novel RET agonist for the treatment of experimental neuropathies. Mol. Pain. 16, 1744806920950866. doi: 10.1177/1744806920950866.
• Ivanova, L., Karelson, M., Dobchev, D.A. (2020). Multitarget Approach to Drug Candidates against Alzheimer’s Disease Related to AChE, SERT, BACE1 and GSK3β Protein Targets. Molecules. 17, 1846. doi: 10.3390/molecules25081846.
• Zukić, S.; Maran, U. (2020). Modelling of antiproliferative activity measured in HeLa cervical cancer cells in a series of xanthene derivatives. SAR QSAR Environ. Res., 31, 905−921. doi: 10.1080/1062936X.2020.1839131.
• Mansouri, K., et al. (2020). CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity. Environ. Health Perspect., 128, 027002. doi: 10.1289/EHP5580.
• Sild, S.; Piir, G.; Neagu, D.; Maran, U. Storing and using quantitative and qualitative structure–activity relationships in the era of toxicological and chemical data expansion, in Big Data in Predictive Toxicology (series Issues in Toxicology), Eds. D. Neagu, A. Richarz, Royal Society of Chemistry, 2020, 185-213.
• Käärik, M.; Arulepp, M.; Käärik, M., Maran, U.; A.; Leis. J. (2020).Characterization and prediction of double-layer capacitance of nanoporous carbon materials using the Quantitative nano-Structure-Property Relationship approach based on experimentally determined porosity descriptors, Carbon. 158, 494-504. https://doi.org/10.1016/ j.carbon.2019.11.017.
• Dinić, J.; Efferth, T.; García-Sosa, A.T.; Grahovac, J.; Padrón, J.M.; Pajeva, I.; Rizzolio, F.; Saponara, S.; Spengle,r G.; Tsakovska, I. (2020). Repurposing old drugs to fight multidrug resistant cancers. Drug Resist Updat. 52:100713. doi: 10.1016/j.drup.2020.100713.
• Kaasik, M.; Kanger, T. (2020). Supramolecular Halogen Bonds in Asymmetric Catalysis. Frontiers in Chemistry, 8. DOI: 10.3389/fchem.2020.599064.
• Kaldas, K.; Preegel, G.; Muldma, K.; Lopp, M. (2020). Wet Air Oxidation of Oil Shales: Kerogen Dissolution and Dicarboxylic Acid Formation. ACS Omega, 5, 35, 22021–22030, pubs.acs.org/doi/10.1021/acsomega.0c01466.
• Konrad, N.; Meniailava, D.; Osadchuk, I.; Adamson, J.; Hasan, M.; Clot, E.; Aav, R.; Borovkov, V.; Kananovich, D. (2020). Supramolecular chirogenesis in zinc porphyrins: complexation with enantiopure thiourea derivatives, binding studies and chirality transfer mechanism. Journal of Porphyrins and Phthalocyanines, 24 (05n07), 840−849.10.1142/S108842461950192X.
• Mishra, K. A.; Adamson, J.; Öeren, M.; Kaabel, S.; Fomitšenko, M.; Aav, R. (2020). Dynamic chiral cyclohexanohemicucurbit[12]uril. Chemical Communications, 56 (93), 14645−14648. DOI: 10.1039/D0CC06817A.
• Osadchuk, I.; Borovkov, V.; Aav, R.; Clot, E. (2020). Benchmarking computational methods and influence of guest conformation on chirogenesis in zinc porphyrin complexes. Physical Chemistry Chemical Physics, 22 (19), 11025−11037. DOI: 10.1039/d0cp00965b.
• Peterson, A.; Ludvig, M-L.; Martõnova, J.; Kaabel, S.; Kerner, P.; Uudsemaa, M.; Trummal, A.; Fomitšenko, M.; Pehk, T.; Aav, R.; Adamson, J. (2020). New oxacalix[4]arene carboxylate detects viologen in protic media. Supramolecular Chemistry, 32 (5), 313−319.10.1080/10610278.2019.1659269.
• Trubitsõn, D.; Kanger, T. (2020). Enantioselective Catalytic Synthesis of N-alkylated Indoles. Symmetry, 12 (7), #1184.10.3390/sym12071184.
• Trubitsõn, D.; Martõnova, J.; Erkman, K.; Metsala, A.; Saame, J.; Kõster, K.; Järving, I.; Leito, I.; Kanger, T. (2020). Enantioselective N-Alkylation of Nitroindoles under Phase-Transfer Catalysis. Synthesis, 52 (07), 1047−1059.10.1055/s-0039-1690751.
• Zubrytski, D. M.; Elek, G. Z.; Lopp, M.; Kananovich, D. G. (2020). Generation of Mixed Anhydrides via Oxidative Fragmentation of Tertiary Cyclopropanols with Phenyliodine(III) Dicarboxylates. Molecules, 26 (1), 140. DOI: 10.3390/molecules26010140.
• Dalidovich, T.; Mishra, K. A.; Shalima, T.; Kudrjašova, M.; Kananovich, D. G.; Aav, R. (2020). Mechanochemical Synthesis of Amides with Uronium-Based Coupling Reagents: A Method for Hexa-amidation of Biotin[6]uril. ACS Sustainable Chemistry & Engineering, 8 (41), 15703−15715. DOI: 10.1021/acssuschemeng.0c05558.
• Hernández, J. G.; Halasz, I.; Crawford, D. E.; Krupicka, M.; Baláž, M.; André, V.; Vella-Zarb, L.; Niidu, A.; García, F.; Maini, L.; Colacino, E. (2020). European Research in Focus: Mechanochemistry for Sustainable Industry (COST Action MechSustInd). Justus Liebig’s Annalen der Chemie, 2020, 8−9. DOI: 10.1002/ejoc.201901718.
• Konik, Y. A.; Kananovich, D. G. (2020). Asymmetric synthesis with titanacyclopropane reagents: From early results to the recent achievements. Tetrahedron Letters. DOI: 10.1016/j.tetlet.2020.152036.
• Lomaka, A.; Tamm, T. (2020). Linearization of moment tensor potentials for multicomponent systems with a preliminary assessment for short-range interaction energy in water dimer and trimer. The Journal of Chemical Physics, 152 (16), #164115. DOI: 10.1063/5.0007473.
• Kananovich, D. G. Copper‐Catalyzed Trifluoromethylation Reactions. In: G. Anilkumar, S. Saranya (Ed.). In: Copper Catalysis in Organic Synthesis (pp. 367−393). Wiley‐VCH.10.1002/9783527826445.ch17. (3.1 publikatsioon).
• Venit T, Dowaidar M, Gestin M, Mahmood SR, Langel Ü, Percipalle P. Transcriptional Profiling Reveals Ribosome Biogenesis, Microtubule Dynamics and Expression of Specific lncRNAs to be Part of a Common Response to Cell-Penetrating Peptides. Biomolecules. 2020 Nov 17;10(11):1567. doi: 10.3390/biom10111567. PMID: 33213097
• Cerrato CP , Kivijärvi T , Tozzi R , Lehto T , Gestin M , Langel Ü . Intracellular delivery of therapeutic antisense oligonucleotides targeting mRNA coding mitochondrial proteins by cell-penetrating peptides. J Mater Chem B. 2020 Dec 21;8(47):10825-10836. doi: 10.1039/d0tb01106a. Epub 2020 Nov 11. PMID: 33174901
• Kurrikoff K, Vunk B, Langel Ü. Status update in the use of cell-penetrating peptides for the delivery of macromolecular therapeutics. Expert Opin Biol Ther. 2020 Sep 23:1-10. doi: 10.1080/14712598.2021.1823368. Online ahead of print. PMID: 32938243
• Carreras-Badosa G, Maslovskaja J, Periyasamy K, Urgard E, Padari K, Vaher H, Tserel L, Gestin M, Kisand K, Arukuusk P, Lou C, Langel Ü, Wengel J, Pooga M, Rebane A. NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation. Biomaterials. 2020 Dec;262:120316. doi: 10.1016/j.biomaterials.2020.120316. Epub 2020 Aug 29. PMID: 32896817
• Gestin M, Helmfors H, Falato L, Lorenzon N, Michalakis FI, Langel Ü. Effect of small molecule signaling in PepFect14 transfection. PLoS One. 2020 Jan 30;15(1):e0228189. doi: 10.1371/journal.pone.0228189. eCollection 2020 PMID: 31999754 (1)
• Arukuusk P, Langel Ü. Synthesis of NickFects, a New Family of CPPs, by Solid-Phase Peptide Synthesis. Methods Mol Biol. 2020;2103:239-247. doi: 10.1007/978-1-0716-0227-0_16. PMID: 31879930