Centre of Excellence In Molecular Cell Engineering
Chemical probes and chemogenetics
WP leader: Mati Karelson
General concept. Specific chemicals for manipulating the properties of cells will be developed.
Projects
- C1. Modulators of viral replication
- C2. Modulators of bacterial gene expression & stress responses
- C3. Chemical probes for improving plant water‐use efficiency
- C4. Methods for designing and synthesizing new chemical probes
Long‐term goal
To create a platform that combines the tools of molecular informatics, computational molecular engineering chemistry, organic synthesis and bioassay engineering for the creation of molecular probes for manipulating biological systems.