18:00 – 18:30

Registration

Location: Conference Centre lobby  (VSpa)

18:30 – 18:45

Opening comments,  Jesper Olsen, UCPH, and Sergo Kasvandik, UT

18:45 – 19:45

Keynote Lectures

Introduction – Jesper Olsen, UCPH

Nurhan Özlü, Koç University, Istanbul

Phosphorylation Dynamics of Keratin Filaments in Dividing Mammalian Cells

Ruedi Aebersold, Professor emeritus ETH, Zurich

MultiOmics or MultiPROTEOmics?

20:00

Dinner

Location: Conference Centre Lobby

08:40 – 09:00

Consortium access activities  –  Kris Gevaert, VIB

09:00 – 11:00

User Sessions (15 min presentations + 5min Q&A)

Chair: Christina Ludwig

09:00 – 09:40

User Session 1

9:00 – 9:20

Towards understanding the aggregation behaviour of immunoglobulin light chains – Alexander K. Buell, Technical University of Denmark

9:20 – 9:40

A proteomic approach to untangle the molecular bases underlying the complex network of plant-microbe interaction – Silvia Proietti, University of Tuscia, Italy

09:40 – 10:00

Coffee break

10:00 – 11.00

User Session 2 (15 min presentations + 5min Q&A)

10:00 – 10:20

Histone post-translational dynamics in response to metabolic changes – Ferdinand von Meyenn, ETH Zurich, Switzerland

10:20 – 10:40

p53 as a regulator of metabolic flexibility in cancer and obesity – Andreas Prokesch, Medical University of Graz, Austria

10:40 – 11:00

Repurposing of a known antipsychotic drug to target arthritogenic synovial fibroblasts and scaffold-based design of novel small molecule therapeutics – Filippos Charalampous, BSRC, Alexander Flemming, Greece

11:00  – 12:00

Industrial Platform Session (15 min presentations + 5min Q&A)

Chair: Michael L. Nielsen

11:00 – 11:20

   CRISPR perturbation screens for the discovery of new targets – Marcus Bantscheff, Cellzome, GSK, Germany

11:20 – 11:40

Advantages of the Unreduced Data in FTMS for Bottom-Up and Top-Down Proteomics  – Yury Tsybin, Spectroswiss, Switzerland

11:40  – 12:00

Simplifying Separation for Clinical Proteomics – Ole Vorm, Evosep, Denmark

12:00 – 13:30

Group photo followed by lunch

Location: Restaurant

13:30  – 15:00

JRA2: Future and Emerging Proteomics Technologies

Chair: Ole Vorm

Overview of JRA2 – Julia Chamot-Rooke, IP

How do we measure success for a top-down proteome experiment – David Tabb, IP

The use of linear ion traps in data-independent acquisition methods for low-input proteomics – Eduard Sabido, CRG

Systems-wide and site-specific characterization of ADP-ribosylation using quantitative mass spectrometry – Michael Lund Nielsen, UCPH

15:00 – 15:30

Coffee break

15:30  – 16:30

JRA4: Proteome Organization: Structural & Spatial Proteomics

Chair: Mariette Matondo

Overview JRA4 – Alexander Leitner, ETH

Computational workflows for spatial proteomics, Lisa Breckels, UCAM

Fast photo-chemical oxidation of proteins for structural characterization of protein complexes, Dmitry Loginov, IMIC

Global in situ analysis of osmolyte mechanisms with LiP-MS, Monika Pepelnjak, ETH

Uncovering the basement membrane landscape through XLMS, Katherine Stevens, UU

17:00  – 18:45

Social activity

19:00

Dinner – Location: Joyce Restaurant VSpa Hotel, 1st floor

08:15 – 08:35

Consortium Objectives Review & Partner Roles – Martina O’Flaherty, UU 

08:35 – 10:05

JRA3: Translational proteomics

Chair: Richard Scheltema

Overview JRA3 – Maarten Altelaar (UU)

Histone PTM and variant analysis from low-abundance clinical samples – Roberta Noberini, IEO

Tumour profiling of HER2+ breast cancer biopsies identifies signatures predictive of treatment response –  Maarten Altelaar, UU

Re-assessment of extracellular vesicle cargo with protein correlation profiling –  Javier Munoz, CNIO

Proteomics workflow to identify tissue leakage proteins in liquid biopsies, Esperanza Fernandez, VIB

10:05 – 10:20

Coffee break

10:20 – 11:50

 JRA1: Bioinformatics to support proteomics

Chair: Javier Muñoz

Overview JRA1 – Juan Antonio, EMBL-EBI

Inferring functional association networks from proteomics data – Sven Degroeve, VIB

Prosit and ProteomicsDB in the context of EPIC-XS  –  Wassim Gabriel, TUM

Intelligent data acquisition for top-down proteomics via ultra-fast mass deconvolution – Kyowon Jeong, EKUT

Ongoing development of open data analysis pipelines for cloud infrastructures  – Juan Antonio, EMBL-EBI

11:50 – 12:05

Closing comments Jesper Olsen, UCPH, and Sergo Kasvandik, UT

Lunch

Location: Vcafe Vspa Hotel

12:45 – 15:00

Shuttle bus from VSpa to Tallinn airport