{"id":41,"date":"2024-04-04T00:39:47","date_gmt":"2024-04-03T21:39:47","guid":{"rendered":"https:\/\/sisu.ut.ee\/lcms_method_validation\/5-trueness\/"},"modified":"2024-04-04T00:41:46","modified_gmt":"2024-04-03T21:41:46","slug":"5-trueness","status":"publish","type":"page","link":"https:\/\/sisu.ut.ee\/lcms_method_validation\/5-trueness\/","title":{"rendered":"5. Trueness"},"content":{"rendered":"<p>\n\tPart 5 of this course focuses\u00a0on the different aspects of trueness\u00a0and its quantitative estimate, bias.\u00a0In <a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/51-bias-and-its-constituents\" target=\"_blank\" rel=\"noopener\">section 5.1<\/a>, the general information and definitions are given. This section, in particular,\u00a0explains the bias constituents (i.e. causes of bias). <a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/52-determining-bias-practice\" target=\"_blank\" rel=\"noopener\">Section 5.2<\/a> addresses the evaluation of (overall) bias in practice. Sections <a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/53-qualitative-estimation-matrix-effect\" target=\"_blank\" rel=\"noopener\">5.3<\/a> and <a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/54-quantitative-estimation-matrix-effect-recovery-process-efficiency\" target=\"_blank\" rel=\"noopener\">5.4<\/a> look at\u00a0more specific aspects related to trueness (bias), specifically in case of LC-MS analysis, including experimental determination of some of the bias constituents.\n<\/p>\n<div>\n<p>\n\t\t\u00a0\n\t<\/p>\n<\/div>\n<p>\n\t<a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/51-bias-and-its-constituents\">5.1.\u00a0Bias and its constituents<\/a>\n<\/p>\n<p>\n\t<a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/52-determining-bias-practice\">5.2. Determining bias in practice<\/a>\n<\/p>\n<p>\n\t<a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/53-qualitative-estimation-matrix-effect\">5.3.\u00a0Qualitative estimation of ionization suppression\/enhancement<\/a>\n<\/p>\n<p>\n\t<a href=\"https:\/\/sisu.ut.ee\/lcms_method_validation\/54-quantitative-estimation-matrix-effect-recovery-process-efficiency\">5.4.\u00a0Quantitative estimation of ionization suppression\u00a0(including ionization suppression reduction)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Part 5 of this course focuses\u00a0on the different aspects of trueness\u00a0and its quantitative estimate, bias.\u00a0In section 5.1, the general information and definitions are given. This section, in particular,\u00a0explains the bias constituents (i.e. causes of bias). Section 5.2 addresses the evaluation &#8230;<\/p>\n","protected":false},"author":60,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-41","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/pages\/41","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/users\/60"}],"replies":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/comments?post=41"}],"version-history":[{"count":1,"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/pages\/41\/revisions"}],"predecessor-version":[{"id":843,"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/pages\/41\/revisions\/843"}],"wp:attachment":[{"href":"https:\/\/sisu.ut.ee\/lcms_method_validation\/wp-json\/wp\/v2\/media?parent=41"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}