{"id":1191,"date":"2024-04-11T14:43:35","date_gmt":"2024-04-11T11:43:35","guid":{"rendered":"https:\/\/sisu.ut.ee\/lcms_method_validation\/self-test-10\/"},"modified":"2024-04-11T14:43:35","modified_gmt":"2024-04-11T11:43:35","slug":"self-test-10","status":"publish","type":"page","link":"https:\/\/sisu.ut.ee\/lcms_method_validation\/self-test-10\/","title":{"rendered":"Self test 10"},"content":{"rendered":"<div id=\"watupro_quiz\" class=\"quiz-area single-page-quiz\">\n<p id=\"submittingExam24\" style=\"display:none;text-align:center;\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/sisu.ut.ee\/wp-content\/plugins\/watupro\/img\/loading.gif\" width=\"16\" height=\"16\"><\/p>\n\n\n\n<form action=\"\" method=\"post\" class=\"quiz-form\" id=\"quiz-24\" enctype=\"multipart\/form-data\">\n<div class=\"watu-question \" id=\"question-1\" style=\";\"><div id=\"questionWrap-1\" class=\"   watupro-question-id-100\">\n\t\t\t<div class=\"question-content\"><div><span class=\"watupro_num\">1. <\/span>Indicate correct statements:<\/div><input type=\"hidden\" name=\"question_id[]\" id=\"qID_1\" value=\"100\" class=\"watupro-question-id\"><input type=\"hidden\" id=\"answerType100\" class=\"answerTypeCnt1\" value=\"checkbox\"><!-- end question-content--><\/div><div class=\"question-choices watupro-choices-columns \" id=\"questionChoices100\"><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-100[]\" id=\"answer-id-249\" class=\"answer   answerof-100 \" value=\"249\"><label for=\"answer-id-249\" id=\"answer-label-249\" class=\" answer\"><span><p>Robustness and ruggedness indicate the analytical method performance during the small variations in chromatography (mobile phase composition, column age, column temperature, etc).<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-100[]\" id=\"answer-id-251\" class=\"answer   answerof-100 \" value=\"251\"><label for=\"answer-id-251\" id=\"answer-label-251\" class=\" answer\"><span><p>Robustness and ruggedness indicate the analytical method performance during the small variations in mass spectrometric conditions (cleanliness of the MS source, changes in the voltages, etc).<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-100[]\" id=\"answer-id-252\" class=\"answer   answerof-100 \" value=\"252\"><label for=\"answer-id-252\" id=\"answer-label-252\" class=\" answer\"><span><p>Robustness and ruggedness are evaluated only during the changes within the same laboratory.<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-100[]\" id=\"answer-id-253\" class=\"answer   answerof-100 \" value=\"253\"><label for=\"answer-id-253\" id=\"answer-label-253\" class=\" answer\"><span><p>In validation guidelines terms robustness and ruggedness are considered to have the same meaning.<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-100[]\" id=\"answer-id-250\" class=\"answer   answerof-100 \" value=\"250\"><label for=\"answer-id-250\" id=\"answer-label-250\" class=\" answer\"><span><p>Robustness and ruggedness indicate the analytical method performance during the small variations in the environmental conditions (season, weather, room temperature, air humidity, etc).<\/p><\/span><\/label><\/div><!-- end question-choices--><\/div><!-- end questionWrap--><\/div><\/div><div class=\"watu-question \" id=\"question-2\" style=\";\"><div id=\"questionWrap-2\" class=\"   watupro-question-id-101\">\n\t\t\t<div class=\"question-content\"><div><span class=\"watupro_num\">2. <\/span>Indicate correct statements:<\/div><input type=\"hidden\" name=\"question_id[]\" id=\"qID_2\" value=\"101\" class=\"watupro-question-id\"><input type=\"hidden\" id=\"answerType101\" class=\"answerTypeCnt2\" value=\"checkbox\"><!-- end question-content--><\/div><div class=\"question-choices watupro-choices-columns \" id=\"questionChoices101\"><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-101[]\" id=\"answer-id-257\" class=\"answer   answerof-101 \" value=\"257\"><label for=\"answer-id-257\" id=\"answer-label-257\" class=\" answer\"><span><p>When used together in the guidelines, robustness and ruggedness are considered to be synonyms.\u00a0<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-101[]\" id=\"answer-id-255\" class=\"answer   answerof-101 \" value=\"255\"><label for=\"answer-id-255\" id=\"answer-label-255\" class=\" answer\"><span><p>Robustness should be used as a parameter characterizing the stability of the method with respect to variations of the internal factors (parameters) of the method.<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-101[]\" id=\"answer-id-254\" class=\"answer   answerof-101 \" value=\"254\"><label for=\"answer-id-254\" id=\"answer-label-254\" class=\" answer\"><span><p>Ruggedness should be used as a parameter evaluating constancy of the results when external factors are changed.<\/p><\/span><\/label><\/div><div class=\"watupro-question-choice  \" dir=\"auto\"><input type=\"checkbox\" name=\"answer-101[]\" id=\"answer-id-256\" class=\"answer   answerof-101 \" value=\"256\"><label for=\"answer-id-256\" id=\"answer-label-256\" class=\" answer\"><span><p>Robustness and ruggedness are the same as decision threshold, detection capacity and measurement uncertainty.<\/p><\/span><\/label><\/div><!-- end question-choices--><\/div><!-- end questionWrap--><\/div><\/div><div style=\"display:none\" id=\"question-3\">\n\t<div class=\"question-content\">\n\t\t<img loading=\"lazy\" decoding=\"async\" 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