{"id":7,"date":"2024-04-03T23:08:58","date_gmt":"2024-04-03T20:08:58","guid":{"rendered":"https:\/\/sisu.ut.ee\/histology\/cerebral-cortex\/"},"modified":"2024-04-09T09:15:47","modified_gmt":"2024-04-09T06:15:47","slug":"cerebral-cortex","status":"publish","type":"page","link":"https:\/\/sisu.ut.ee\/histology\/cerebral-cortex\/","title":{"rendered":"The cerebral cortex"},"content":{"rendered":"<p><strong>The cerebral hemispheres<\/strong> consist of a convoluted cortex of gray matter (thickness around 3 mm, total surface area 1.2-2.6 m<sup>2<\/sup>) overlying the central medullary mass of white matter, which conveys fibers between different parts of the cortex and from other parts of central nervous system. The surface area of the cortex is increased by its convolutions, which are separated by fissures. The cerebral cortex consists of neurons, nerve fibers and neuroglia.<\/p>\n<p><strong>The cerebral cortex<\/strong> (neocortex) consists of six layers (in human the primitive arrangement into three layers persists only in the olfactory cortex and the cortical part of the limbic system in the temporal lobe). Most of the neurons in the cerebral cortex are arranged vertically and most abundant neurons are the efferent pyramidal cells (very large giant pyramidal cells found in the layer V of the regions of the motor cortex are called Betz cells).<\/p>\n<p>The <strong>six layers<\/strong> of the cerebral cortex are:<\/p>\n<ul>\n<li><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">I. Molecular layer (<\/span><em style=\"line-height: 1.6em;\">lamina molecularis<\/em><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">) \u2013 consists only a few nerve cells<\/span><\/li>\n<li><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">II. External granular layer (<\/span><em style=\"line-height: 1.6em;\">lamina granularis externa<\/em><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">) \u2013 relatively thin layer consisting of numerous small, densely packed neurons<\/span><\/li>\n<li><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">III. Pyramidal layer or external pyramidal layer (<\/span><em style=\"line-height: 1.6em;\">lamina pyramidalis externa<\/em><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">) \u2013 is composed of medium-sized pyramidal nerve cells<\/span><\/li>\n<li><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">IV. Inner granular layer (<\/span><em style=\"line-height: 1.6em;\">lamina granularis interna<\/em><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">) \u2013 contains small, irregularily shaped nerve cells<\/span><\/li>\n<li><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">V. Ganglionic or inner pyramidal layer (<\/span><em style=\"line-height: 1.6em;\">lamina pyramidalis interna<\/em><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">) \u2013 includes large pyramidal cells<\/span><\/li>\n<li><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">VI. Multiform layer (<\/span><em style=\"line-height: 1.6em;\">lamina multiformis<\/em><span style=\"line-height: 1.6em;\" data-mce-mark=\"1\">) \u2013 small polymorphic and fusiform nerve cells<\/span><\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"356\" height=\"488\" class=\"alignnone wp-image-21 aligncenter\" style=\"margin-left: auto; margin-right: auto;\" title=\"celebrar_cortex.png\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/16\/celebrar_cortex.png\" alt=\"celebrar_cortex.png\" srcset=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/16\/celebrar_cortex.png 356w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/16\/celebrar_cortex-219x300.png 219w\" sizes=\"auto, (max-width: 356px) 100vw, 356px\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"565\" height=\"777\" class=\"wp-image-22 aligncenter\" style=\"margin-left: auto; margin-right: auto;\" title=\"celebrar_cortex2-3.png\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/16\/celebrar_cortex2-3.png\" alt=\"celebrar_cortex2-3.png\" srcset=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/16\/celebrar_cortex2-3.png 565w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/16\/celebrar_cortex2-3-218x300.png 218w\" sizes=\"auto, (max-width: 565px) 100vw, 565px\"><\/p>\n<h6>Nota bene! Six major layers are recognized in the cerebral cortex. These layers are differently developed in various regions of the cerebral cortex, e.g. pyramidal layers are more developed in the motor centres and granular layers in sensory centres of the cerebral cortex.<\/h6>\n","protected":false},"excerpt":{"rendered":"<p>The cerebral hemispheres consist of a convoluted cortex of gray matter (thickness around 3 mm, total surface area 1.2-2.6 m2) overlying the central medullary mass of white matter, which conveys fibers between different parts of the cortex and from other &#8230;<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-7","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/pages\/7","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/comments?post=7"}],"version-history":[{"count":3,"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/pages\/7\/revisions"}],"predecessor-version":[{"id":82,"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/pages\/7\/revisions\/82"}],"wp:attachment":[{"href":"https:\/\/sisu.ut.ee\/histology\/wp-json\/wp\/v2\/media?parent=7"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}