{"id":4,"date":"2024-04-04T05:54:33","date_gmt":"2024-04-04T02:54:33","guid":{"rendered":"https:\/\/sisu.ut.ee\/genmed\/en\/"},"modified":"2024-04-29T16:20:34","modified_gmt":"2024-04-29T13:20:34","slug":"en","status":"publish","type":"page","link":"https:\/\/sisu.ut.ee\/genmed\/en\/?lang=en","title":{"rendered":"GenMed \u2013 creating IT infrastructure for nation-wide personalised medicine"},"content":{"rendered":"<p><img decoding=\"async\" style=\"width: 173px; height: 100px; float: right; margin-top: 20px; margin-bottom: 20px;\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/erf_logo.jpg\" alt=\"ERF\" data-file_info=\"%7B%22fid%22:46988,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><span style=\"font-size: revert; font-weight: var(--bs-body-font-weight); text-align: var(--bs-body-text-align);\">The aim of the GenMed project is to build the necessary <\/span><strong style=\"font-size: revert; text-align: var(--bs-body-text-align);\">IT infrastructure in Estonia to apply personalised medicine principles in clinical practice<\/strong><span style=\"font-size: revert; font-weight: var(--bs-body-font-weight); text-align: var(--bs-body-text-align);\"> so that personalised medicine could benefit all people in Estonia. In the course of the project, solutions for pharmacogenetics and polygenic risk scores are introduced as part of the national e-health system. This results in suggestions in prescriptions about drug dosage, as well as indicating the inherited risk of diabetes and heart disease based on the patient\u2019s DNA.<\/span><\/p>\n<table class=\"table table-hover\" border=\"0\" cellspacing=\"0\" cellpadding=\"5\">\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/icpermed.jpg\" alt=\"Alt\" width=\"400\" height=\"279\" data-file_info=\"%7B%22fid%22:46961,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><\/td>\n<td><strong>The algorithm of pharmacogenetic recommendations<\/strong> is based on the research of the University of Tartu, which was selected by the International Personnel Medicine Consortium (ICPerMed) as the best personalised medicine practice in 2019. The algorithm analyzes the patient\u2019s gene data, and if the patient has any medication for which the amount of the drug should be changed, it informs the doctor.<\/td>\n<\/tr>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/prs.jpg\" alt=\"Pol\u00fcgeense riskiskoori p\u00f5hjal antava tagasiside n\u00e4idis\" width=\"400\" height=\"288\" data-file_info=\"%7B%22fid%22:46962,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><\/td>\n<td>\n<strong>Polygenic risk scores<\/strong> analyse a person\u2019s thousands of genetic traits and assess a person\u2019s inherited risk of developing chronic diseases. The GenMed project uses the risk scores for type 2 diabetes and cardiovascular diseases previously developed by the Institute of Genomics.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Project duration<\/h2>\n<p>From 2019 until 2022.<\/p>\n<h2>Parties involved<\/h2>\n<p>The IT solution of the project is coordinated and implemented by the <strong>Centre of Personalised Medicine and Health Informatics of the University of Tartu<\/strong> (Institute of Computer Science together with the Institute of Genomics). The development of the IT solution is led by <strong>Prof. Jaak Vilo<\/strong> with a team that includes top scientists and specialists in their field. Competencies have been developed in cooperation with the BIIT Bioinformatics research group of the University of Tartu and the data science company STACC. In addition, the Ministry of Social Affairs, the Institute for Health <span style=\"font-size: 14px;\">Development, the Estonian Health Insurance Fund and the Health and Welfare Information Systems Center participate in the project<\/span><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" width=\"2671\" height=\"904\" class=\"alignnone wp-image-25\" style=\"width: 295px; height: 100px;\" title=\"ut_logo_eng.png\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng.png\" alt=\"University of Tartu\" srcset=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng.png 2671w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng-300x102.png 300w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng-1024x347.png 1024w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng-768x260.png 768w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng-1536x520.png 1536w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng-2048x693.png 2048w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/ut_logo_eng-1920x650.png 1920w\" sizes=\"auto, (max-width: 2671px) 100vw, 2671px\"><img loading=\"lazy\" decoding=\"async\" width=\"5198\" height=\"1390\" class=\"alignnone wp-image-23\" style=\"width: 374px; height: 100px;\" title=\"arvutiteaduse_instituut_eng_sinine.png\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine.png\" alt=\"Institute of Computer Science\" srcset=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine.png 5198w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine-300x80.png 300w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine-1024x274.png 1024w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine-768x205.png 768w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine-1536x411.png 1536w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine-2048x548.png 2048w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/arvutiteaduse_instituut_eng_sinine-1920x513.png 1920w\" sizes=\"auto, (max-width: 5198px) 100vw, 5198px\"><span style=\"font-size: 14px;\">\u00a0<\/span><img loading=\"lazy\" decoding=\"async\" width=\"1650\" height=\"300\" class=\"alignnone wp-image-22\" style=\"width: 330px; height: 60px;\" title=\"personaalmed_eng.png\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/personaalmed_eng.png\" alt=\"Centre of personalised medicine and health informatics\" srcset=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/personaalmed_eng.png 1650w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/personaalmed_eng-300x55.png 300w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/personaalmed_eng-1024x186.png 1024w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/personaalmed_eng-768x140.png 768w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/personaalmed_eng-1536x279.png 1536w\" sizes=\"auto, (max-width: 1650px) 100vw, 1650px\"><span style=\"font-size: 14px;\"> \u00a0\u00a0<\/span><img decoding=\"async\" style=\"width: 167px; height: 60px;\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/biit.png\" alt=\"BIIT\" data-file_info=\"%7B%22fid%22:%2246981%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"5198\" height=\"1390\" class=\"alignnone wp-image-24\" style=\"width: 374px; height: 100px;\" title=\"genoomika_instituut_eng_sinine.png\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine.png\" alt=\"Institute of Genomics\" srcset=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine.png 5198w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine-300x80.png 300w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine-1024x274.png 1024w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine-768x205.png 768w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine-1536x411.png 1536w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine-2048x548.png 2048w, https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genoomika_instituut_eng_sinine-1920x513.png 1920w\" sizes=\"auto, (max-width: 5198px) 100vw, 5198px\"><img decoding=\"async\" style=\"width: 333px; height: 60px;\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/tai_logo.png\" alt=\"Tervise Arengu Instituudi logo\" data-file_info=\"%7B%22fid%22:%2246966%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/tehik_logo.png\" alt=\"TEHIK logo\" width=\"218\" height=\"100\" data-file_info=\"%7B%22fid%22:%2246964%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/hk_logo_est.png\" alt=\"Eesti Haigekassa logo\" width=\"263\" height=\"100\" data-file_info=\"%7B%22fid%22:%2246967%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><img decoding=\"async\" style=\"width: 233px; height: 80px;\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/stacc.png\" alt=\"STACC\" data-file_info=\"%7B%22fid%22:%2246983%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><\/p>\n<h2>One of the project\u2019s first meetings<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/genmed.jpg\" alt=\"GenMed 15.04.2019\" width=\"1828\" height=\"1120\" data-file_info=\"%7B%22fid%22:%2247160%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><\/p>\n<h2>Funded by<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/sotsmin_3lovi_est.png\" alt=\"Sotsiaalministeeriumi logo\" width=\"250\" height=\"100\" data-file_info=\"%7B%22fid%22:%2246963%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><img decoding=\"async\" style=\"width: 173px; height: 100px;\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/erf_logo.jpg\" alt=\"ERF\" data-file_info=\"%7B%22fid%22:%2246988%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\"><\/p>\n<h2>Contact<\/h2>\n<table class=\"table table-hover\" border=\"0\" cellspacing=\"0\" cellpadding=\"5\">\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" title=\"\" src=\"https:\/\/sisu.ut.ee\/wp-content\/uploads\/sites\/422\/jaakvilo.jpg\" alt=\"Jaak Vilo\" width=\"100\" height=\"100\" data-file_info=\"%7B%22fid%22:%2246992%22,%22view_mode%22:%22default%22,%22type%22:%22media%22%7D\">\n<p><strong>Jaak Vilo<\/strong><br>\n<a title=\"\" href=\"vilo@ut.ee\" target=\"_blank\" rel=\"noopener\" data-url=\"\/genmed\/mailto:vilo@ut.ee\">vilo@ut.ee<\/a><\/p>\n<p><strong>Personaalmeditsiini ja terviseinformaatika keskus <\/strong>(room 2042)<br>\nInstitute of Computer Science<br>\nUniversity of Tartu<br>\nNarva mnt 18<br>\n51009 Tartu<br>\nEstonia<\/p><\/td>\n<td><div class=\"video-placeholder-wrapper video-placeholder-wrapper--fixed\" style=\"height: 450px;\">\n\t\t\t    <div class=\"video-placeholder d-flex justify-content-center align-items-center\">\n\t\t\t        <div class=\"overlay text-white p-2 w-100 text-center d-block justify-content-center align-items-center\">\n\t\t\t            <div>Kolmandate osapoolte sisu n\u00e4gemiseks palun n\u00f5ustu k\u00fcpsistega.<\/div>\n\t\t\t            <button class=\"btn btn-secondary btn-sm mt-1 consent-change\">Muuda n\u00f5usolekut<\/button>\n\t\t\t        <\/div>\n\t\t\t    <\/div>\n\t\t\t<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>The aim of the GenMed project is to build the necessary IT infrastructure in Estonia to apply personalised medicine principles in clinical practice so that personalised medicine could benefit all people in Estonia. In the course of the project, solutions &#8230;<\/p>\n","protected":false},"author":223,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-4","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/pages\/4","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/users\/223"}],"replies":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/comments?post=4"}],"version-history":[{"count":2,"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/pages\/4\/revisions"}],"predecessor-version":[{"id":57,"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/pages\/4\/revisions\/57"}],"wp:attachment":[{"href":"https:\/\/sisu.ut.ee\/genmed\/wp-json\/wp\/v2\/media?parent=4"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}