\n\tOn this page we post\u00a0our project publications divided into four categories:\u00a0Research publications, Press releases, Public deliverables, Media.\n<\/p>\n
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\n\tEssers, R., Lebedev, I.N., Kurg, A. et al. Prevalence of chromosomal alterations in first-trimester spontaneous pregnancy loss. Nature Medicine, 29(12), 3233\u20133242. https:\/\/doi.org\/10.1038\/s41591-023-02645-5<\/a>\n<\/p>\n\n\tLawarde, A., Rahmani, E. S., Nath, A., Lav\u00f5gina, D., Jaal, J., Salumets, A., & Modhukur, V. (2024). ExplORRNet: An interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers. Non-coding RNA Research, 9(1), 125\u2013140. https:\/\/doi.org\/10.1016\/j.ncrna.2023.10.006<\/a>\n<\/p>\n\n\tMinha, S., Vaikj\u00e4rv, R., Parm, \u00dc., Kasen\u00f5mm, P., K\u00f5ljalg, S., Sepp, E., Jaagura, M., Salumets, A., \u0160t\u0161epetova, J., & M\u00e4ndar, R. (2023). Unveiling the etiology of peritonsillar abscess using next generation sequencing. Annals of Clinical Microbiology and Antimicrobials, 22(1). https:\/\/doi.org\/10.1186\/s12941-023-00649-0<\/a>\n<\/p>\n\n\tKhatun, M., Lundin, K., Naillat, F., Loog, L., Saarela, U., Tuuri, T., Salumets, A., Piltonen, T., & Tapanainen, J. S. (2023). Induced pluripotent stem cells as a possible approach for exploring the pathophysiology of polycystic ovary syndrome (PCOS). Stem Cell Reviews and Reports. https:\/\/doi.org\/10.1007\/s12015-023-10627-w<\/a>\n<\/p>\n\n\tTarvainen, I., Soto, D. A., Laws, M. J., Bj\u00f6rvang, R. D., Damdimopoulos, A., Roos, K., Li, T., Kramer, S., Li, Z., Lavogina, D., Visser, N., Kallak, T. K., Lager, S., Gidl\u00f6f, S., Edlund, E., Papaikonomou, K., \u00d6berg, M., Olovsson, M., Salumets, A., Velthut-Meikas, A., \u00a0Flaws, J.A., Damdimopoulou, P. (2023). Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro. Reproductive Toxicology, 119, 108393. https:\/\/doi.org\/10.1016\/j.reprotox.2023.108393<\/a>\n<\/p>\n\n\tGoel, R., Modhukur, V., T\u00e4\u00e4r, K., Salumets, A., Sharma, R., & Peters, M. (2023). Users\u2019 Concerns about endometriosis on social Media: Sentiment analysis and topic Modeling study. Journal of Medical Internet Research, 25, e45381. https:\/\/doi.org\/10.2196\/45381<\/a>\n<\/p>\n\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tLawarde, A., Rahmani, E. S., Nath, A., Lav\u00f5gina, D., Jaal, J., Salumets, A., & Modhukur, V. (2024). ExplORRNet: An interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers. Non-coding RNA Research, 9(1), 125\u2013140. https:\/\/doi.org\/10.1016\/j.ncrna.2023.10.006<\/a>\n<\/p>\n\n\tMinha, S., Vaikj\u00e4rv, R., Parm, \u00dc., Kasen\u00f5mm, P., K\u00f5ljalg, S., Sepp, E., Jaagura, M., Salumets, A., \u0160t\u0161epetova, J., & M\u00e4ndar, R. (2023). Unveiling the etiology of peritonsillar abscess using next generation sequencing. Annals of Clinical Microbiology and Antimicrobials, 22(1). https:\/\/doi.org\/10.1186\/s12941-023-00649-0<\/a>\n<\/p>\n\n\tKhatun, M., Lundin, K., Naillat, F., Loog, L., Saarela, U., Tuuri, T., Salumets, A., Piltonen, T., & Tapanainen, J. S. (2023). Induced pluripotent stem cells as a possible approach for exploring the pathophysiology of polycystic ovary syndrome (PCOS). Stem Cell Reviews and Reports. https:\/\/doi.org\/10.1007\/s12015-023-10627-w<\/a>\n<\/p>\n\n\tTarvainen, I., Soto, D. A., Laws, M. J., Bj\u00f6rvang, R. D., Damdimopoulos, A., Roos, K., Li, T., Kramer, S., Li, Z., Lavogina, D., Visser, N., Kallak, T. K., Lager, S., Gidl\u00f6f, S., Edlund, E., Papaikonomou, K., \u00d6berg, M., Olovsson, M., Salumets, A., Velthut-Meikas, A., \u00a0Flaws, J.A., Damdimopoulou, P. (2023). Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro. Reproductive Toxicology, 119, 108393. https:\/\/doi.org\/10.1016\/j.reprotox.2023.108393<\/a>\n<\/p>\n\n\tGoel, R., Modhukur, V., T\u00e4\u00e4r, K., Salumets, A., Sharma, R., & Peters, M. (2023). Users\u2019 Concerns about endometriosis on social Media: Sentiment analysis and topic Modeling study. Journal of Medical Internet Research, 25, e45381. https:\/\/doi.org\/10.2196\/45381<\/a>\n<\/p>\n\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tMinha, S., Vaikj\u00e4rv, R., Parm, \u00dc., Kasen\u00f5mm, P., K\u00f5ljalg, S., Sepp, E., Jaagura, M., Salumets, A., \u0160t\u0161epetova, J., & M\u00e4ndar, R. (2023). Unveiling the etiology of peritonsillar abscess using next generation sequencing. Annals of Clinical Microbiology and Antimicrobials, 22(1). https:\/\/doi.org\/10.1186\/s12941-023-00649-0<\/a>\n<\/p>\n\n\tKhatun, M., Lundin, K., Naillat, F., Loog, L., Saarela, U., Tuuri, T., Salumets, A., Piltonen, T., & Tapanainen, J. S. (2023). Induced pluripotent stem cells as a possible approach for exploring the pathophysiology of polycystic ovary syndrome (PCOS). Stem Cell Reviews and Reports. https:\/\/doi.org\/10.1007\/s12015-023-10627-w<\/a>\n<\/p>\n\n\tTarvainen, I., Soto, D. A., Laws, M. J., Bj\u00f6rvang, R. D., Damdimopoulos, A., Roos, K., Li, T., Kramer, S., Li, Z., Lavogina, D., Visser, N., Kallak, T. K., Lager, S., Gidl\u00f6f, S., Edlund, E., Papaikonomou, K., \u00d6berg, M., Olovsson, M., Salumets, A., Velthut-Meikas, A., \u00a0Flaws, J.A., Damdimopoulou, P. (2023). Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro. Reproductive Toxicology, 119, 108393. https:\/\/doi.org\/10.1016\/j.reprotox.2023.108393<\/a>\n<\/p>\n\n\tGoel, R., Modhukur, V., T\u00e4\u00e4r, K., Salumets, A., Sharma, R., & Peters, M. (2023). Users\u2019 Concerns about endometriosis on social Media: Sentiment analysis and topic Modeling study. Journal of Medical Internet Research, 25, e45381. https:\/\/doi.org\/10.2196\/45381<\/a>\n<\/p>\n\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKhatun, M., Lundin, K., Naillat, F., Loog, L., Saarela, U., Tuuri, T., Salumets, A., Piltonen, T., & Tapanainen, J. S. (2023). Induced pluripotent stem cells as a possible approach for exploring the pathophysiology of polycystic ovary syndrome (PCOS). Stem Cell Reviews and Reports. https:\/\/doi.org\/10.1007\/s12015-023-10627-w<\/a>\n<\/p>\n\n\tTarvainen, I., Soto, D. A., Laws, M. J., Bj\u00f6rvang, R. D., Damdimopoulos, A., Roos, K., Li, T., Kramer, S., Li, Z., Lavogina, D., Visser, N., Kallak, T. K., Lager, S., Gidl\u00f6f, S., Edlund, E., Papaikonomou, K., \u00d6berg, M., Olovsson, M., Salumets, A., Velthut-Meikas, A., \u00a0Flaws, J.A., Damdimopoulou, P. (2023). Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro. Reproductive Toxicology, 119, 108393. https:\/\/doi.org\/10.1016\/j.reprotox.2023.108393<\/a>\n<\/p>\n\n\tGoel, R., Modhukur, V., T\u00e4\u00e4r, K., Salumets, A., Sharma, R., & Peters, M. (2023). Users\u2019 Concerns about endometriosis on social Media: Sentiment analysis and topic Modeling study. Journal of Medical Internet Research, 25, e45381. https:\/\/doi.org\/10.2196\/45381<\/a>\n<\/p>\n\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tTarvainen, I., Soto, D. A., Laws, M. J., Bj\u00f6rvang, R. D., Damdimopoulos, A., Roos, K., Li, T., Kramer, S., Li, Z., Lavogina, D., Visser, N., Kallak, T. K., Lager, S., Gidl\u00f6f, S., Edlund, E., Papaikonomou, K., \u00d6berg, M., Olovsson, M., Salumets, A., Velthut-Meikas, A., \u00a0Flaws, J.A., Damdimopoulou, P. (2023). Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro. Reproductive Toxicology, 119, 108393. https:\/\/doi.org\/10.1016\/j.reprotox.2023.108393<\/a>\n<\/p>\n\n\tGoel, R., Modhukur, V., T\u00e4\u00e4r, K., Salumets, A., Sharma, R., & Peters, M. (2023). Users\u2019 Concerns about endometriosis on social Media: Sentiment analysis and topic Modeling study. Journal of Medical Internet Research, 25, e45381. https:\/\/doi.org\/10.2196\/45381<\/a>\n<\/p>\n\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tGoel, R., Modhukur, V., T\u00e4\u00e4r, K., Salumets, A., Sharma, R., & Peters, M. (2023). Users\u2019 Concerns about endometriosis on social Media: Sentiment analysis and topic Modeling study. Journal of Medical Internet Research, 25, e45381. https:\/\/doi.org\/10.2196\/45381<\/a>\n<\/p>\n\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tPathare, A. D. S., Loid, M., Saare, M., Gidl\u00f6f, S., Esteki, M. Z., Acharya, G., Peters, M., & Salumets, A. (2023). Endometrial receptivity in women of advanced age: an underrated factor in infertility. Human Reproduction Update. https:\/\/doi.org\/10.1093\/humupd\/dmad019<\/a>\n<\/p>\n\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tHassan, J., Knuus, K., Lahtinen, A., Rooda, I., Otala, M., Tuuri, T., Gidl\u00f6f, S., Edlund, E., Menezes, J., Malmros, J., Bystr\u00f6m, P., Sundin, M., Langenski\u00f6ld, C., Vogt, H., Frisk, P., Petersen, C., Damdimopoulou, P., & Jahnukainen, K. (2023). Reference standards for follicle density in ovarian cortex from birth to sexual maturity. Reproductive Biomedicine Online, 103287. https:\/\/doi.org\/10.1016\/j.rbmo.2023.103287<\/a>\n<\/p>\n\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tPathare, A. D. S., Saare, M., Meltsov, A., Lawarde, A., Modhukur, V., Kalinina, A., Sekavin, A., Kukushkina, V., Karro, H., Salumets, A., & Peters, M. (2023). The cervical transcriptome changes during the menstrual cycle but does not predict the window of implantation. Frontiers in Reproductive Health, 5. https:\/\/doi.org\/10.3389\/frph.2023.1224919<\/a>\n<\/p>\n\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKov\u00e1cs, Z., Reidy, F., Glover, L., McAuliffe, F. M., St\u00f6ckmann, H., Kilbane, M., Twomey, P. J., Peters, M., Saare, M., Rudd, P. M., Utt, M., Wingfield, M., Salumets, A., & Saldova, R. (2023). N-glycans from serum IgG and total serum glycoproteins specific for endometriosis. Scientific Reports, 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37421-5<\/a>\n<\/p>\n\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKoort, K., S\u00f5sa, K., T\u00fcrk, S., Lapp, E., Talving, E., Karits, P., Rosenstein, K., Jaagura, M., Sekavin, A., S\u00f5ritsa, D., Haldre, K., Karro, H., Korrovits, P., Salumets, A. and M\u00e4ndar, R. Lactobacillus crispatus-dominated vaginal microbiome and Acinetobacter-dominated seminal microbiome support beneficial ART outcome. Acta Obstet Gynecol Scand. 2023; 102: 921-934. https:\/\/doi.org\/10.1111\/aogs.14598<\/a>\n<\/p>\n\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tBrentjens, L. S., Obukhova, D., Hartog, J. D., Delvoux, B., Koskivuori, J., Auriola, S., H\u00e4kkinen, Bui, B., Van Hoogenhuijze, N., Mackens, S., Mol, F., De Bruin, J., Besselink, D., Teklenburg, G., Kukushkina, V., Salumets, A., Broekmans, F., Van Golde, R., Esteki, M. Z., & Romano, A. (2023). An integrative analysis of endometrial steroid metabolism and transcriptome in relation to endometrial receptivity in in vitro fertilization patients. F&S Science. https:\/\/doi.org\/10.1016\/j.xfss.2023.04.003<\/a>\n<\/p>\n\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tAltm\u00e4e, S., Sola-Leyva, A. and Salumets, A. (2023). Artificial intelligence in scientific writing: a friend or a foe? Reproductive Biomedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2023.04.009<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tRahmioglu, N., Mortlock, S., Ghiasi, M., M\u00f8ller, P.L., Stefansdottir, L., Galarneau, G., Turman, C., Danning, R., Law, M.H., Sapkota, Y., Christofidou, P., Skarp, S., Giri, A., Banasik, K., Krassowski, M., Lepamets, M., Marciniak, B., N\u00f5ukas, M., Perro, D. and Sliz, E. (2023). The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nature Genetics,\u00a055(3), pp.423\u2013436. https:\/\/doi.org\/10.1038\/s41588-023-01323-z<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tM\u00e4ndar, R., S\u00f5erunurk, G., \u0160t\u0161epetova, J., Smidt, I., R\u00f6\u00f6p, T., K\u00f5ljalg, S., Saare, M., Ausmees, K., Le, D. D., Jaagura, M., Piiskop, S., Tamm, H., & Salumets, A. (2023). Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Beneficial Microbes, 14(2), 143\u2013152. https:\/\/doi.org\/10.3920\/bm2022.0091<\/a>\n<\/p>\n\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tLauda\u0144ski, P., Rogalska, G., Warzecha, D., Lipa, M., Ma\u0144ka, G., Kiecka, M., Spaczy\u0144ski, R., Piekarski, P., Banaszewska, B., Jakimiuk, A., Issat, T., Rokita, W., M\u0142odawski, J., Szubert, M., Sieroszewski, P., Raba, G., Szczupak, K., Kluz, T., Kluza, M. and Neuman, T. (2023). Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Human Reproduction, 38(4), pp.629\u2013643. https:\/\/doi.org\/10.1093\/humrep\/dead011<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tLi, T., Vazakidou, P., Leonards, P., Damdimopoulos, A., Panagiotou, E., Arnelo, C., Jansson, K., Pettersson, K., Papaikonomou, K., Van Duursen, M. B., & Damdimopoulou, P. (2023). Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models. Toxicology, 485, 153425. https:\/\/doi.org\/10.1016\/j.tox.2023.153425<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F. and Damdimopoulou, P. (2023). The Continued Absence of Functional Germline Stem Cells in Adult Ovaries. Stem Cells, 41(2), pp.105\u2013110. https:\/\/doi.org\/10.1093\/stmcls\/sxac070<\/a>\n<\/p>\n\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tYoshihara, M., Wagner, M., Damdimopoulos, A., Zhao, C., Petropoulos, S., Katayama, S., Kere, J., Lanner, F., & Damdimopoulou, P. (2023). In reply: Revisiting claims of the continued absence of functional germline stem cells in adult ovaries. Stem Cells, 41(2), 205\u2013206. https:\/\/doi.org\/10.1093\/stmcls\/sxac084<\/a>\n<\/p>\n\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tBellavia, A., Zou, R., Bj\u00f6rvang, R. D., Roos, K., Sjunnesson, Y., Hallberg, I., Holte, J., Pikki, A., Lenters, V., Portengen, L., Koekkoek, J., Lamoree, M., Van Duursen, M., Vermeulen, R., Salumets, A., Velthut-Meikas, A., & Damdimopoulou, P. (2023). Association between chemical mixtures and female fertility in women undergoing assisted reproduction in Sweden and Estonia. Environmental Research, 216, 114447.https:\/\/doi.org\/10.1016\/j.envres.2022.114447<\/a>\u00a0\n<\/p>\n\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tAuvinen, P., Vehvil\u00e4inen, J., Marjonen, H., Modhukur, V., Sokka, J., Wall\u00e9n, E., R\u00e4m\u00f6, K., Ahola, L., Salumets, A., Otonkoski, T., Skottman, H., Ollikainen, M., Trokovic, R., Kahila, H. and Kaminen-Ahola, N. (2022). Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders. BMC Medicine, 20(1). https:\/\/doi.org\/10.1186\/s12916-022-02699-1<\/a>\n<\/p>\n\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tNaydenov, M., Nikolova, M., Apostolov, A., Glogovitis, I., Salumets, A., Baev, V. and Yahubyan, G. (2022). The Dynamics of miR-449a\/c Expression during Uterine Cycles Are Associated with Endometrial Development. Biology, 12(1), p.55. https:\/\/doi.org\/10.3390\/biology12010055<\/a>\n<\/p>\n\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tRoos, K., Rooda, I., Keif, R. S., Liivrand, M., Smolander, O. P., Salumets, A., & Velthut-Meikas, A. (2022). Single-cell RNA-seq analysis and cell-cluster deconvolution of the human preovulatory follicular fluid cells provide insights into the pathophysiology of ovarian hyporesponse. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.945347<\/a>\n<\/p>\n\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKoel, M., Krjut\u0161kov, K., Saare, M., Samuel, K., Lubenets, D., Katayama, S., Einarsdottir, E., Vargas, E., Sola-Leyva, A., Lalitkumar, P. G., Gemzell-Danielsson, K., Blesa, D., Simon, C., Lanner, F., Kere, J., Salumets, A., & Altm\u00e4e, S. (2022). Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo-endometrium interplay. Human Reproduction Open. https:\/\/doi.org\/10.1093\/hropen\/hoac043<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKoeck, R.M., Busato, F., Tost, J., Zandstra, H., Remy, S., Langie, S., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., Zamani Esteki, M. and van Montfoort, A.P.A. (2022). At age 9, the methylome of assisted reproductive technology children that underwent embryo culture in different media is not significantly different on a genome-wide scale. Human Reproduction, 37(11), pp.2709\u20132721. https:\/\/doi.org\/10.1093\/humrep\/deac213<\/a>\u00a0\n<\/p>\n\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tvan Dijk, W., Derks, K., Dr\u00fcsedau, M., Meekels, J., Koeck, R., Essers, R., Dreesen, J., Coonen, E., de Die-Smulders, C., Stevens, S.J.C., Brunner, H.G., van den Wijngaard, A., Paulussen, A.D.C. and Zamani Esteki, M. (2022). Embryo tracking system for high-throughput sequencing-based preimplantation genetic testing. Human Reproduction, 37(11), pp.2700\u20132708. https:\/\/doi.org\/10.1093\/humrep\/deac208<\/a>\n<\/p>\n\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tLavogina, D., Visser, N., Samuel, K., Davey, E., Bj\u00f6rvang, R. D., Hassan, J., Koponen, J., Rantakokko, P., Kiviranta, H., Rinken, A., Olovsson, M., Salumets, A., & Damdimopoulou, P. (2022). Endocrine disrupting chemicals interfere with decidualization of human primary endometrial stromal cells in vitro. Frontiers in Endocrinology, 13. https:\/\/doi.org\/10.3389\/fendo.2022.903505<\/a>\u00a0\n<\/p>\n\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tM\u00e9ar, L., Sutantiwanichkul, T., \u00d6stman, J., Damdimopoulou, P., & Lindskog, C. (2022). Spatial proteomics for further exploration of missing proteins: a case study of the ovary. Journal of Proteome Research, 22(4), 1071\u20131079. https:\/\/doi.org\/10.1021\/acs.jproteome.2c00392<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tPanagiotou, E.M., Draskau, M.K., Li, T., Hirschberg, A., Svingen, T. and Damdimopoulou, P. (2022). AOP key event relationship report: Linking decreased androgen receptor activation with decreased granulosa cell proliferation of gonadotropin-independent follicles. Reproductive Toxicology, 112, pp.136\u2013147. https:\/\/doi.org\/10.1016\/j.reprotox.2022.07.004<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKoeck, R.M., Busato, F., Tost, J., Consten, D., van Echten-Arends, J., Mastenbroek, S., Wurth, Y., Remy, S., Langie, S., Nawrot, T.S., Plusquin, M., Alfano, R., Bijnens, E.M., Gielen, M., van Golde, R., Dumoulin, J.C.M., Brunner, H., van Montfoort, A.P.A. and Zamani Esteki, M. (2022). Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences. npj Genomic Medicine, 7(1). https:\/\/doi.org\/10.1038\/s41525-022-00310-3<\/a>\u00a0\n<\/p>\n\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tPeters, M., Mikeltadze, I., Karro, H., Saare, M., Metspalu, A., Nelis, M., Milani, L., Hudjashov, G., Esko, T., Salumets, A., M\u00e4gi, R. and Laisk, T. (2022). Endometriosis and irritable bowel syndrome: similarities and differences in the spectrum of comorbidities. Human Reproduction, 37(9), pp.2186\u20132196. https:\/\/doi.org\/10.1093\/humrep\/deac140<\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tSaare, M., Lawarde, A., Modhukur, V., Mikeltadze, I., Karro, H., Minajeva, A., Salumets, A., & Peters, M. (2022). The expression pattern of endometrial receptivity genes is desynchronized between endometrium and matched endometriomas. Reproductive BioMedicine Online. https:\/\/doi.org\/10.1016\/j.rbmo.2022.05.028<\/a>\n<\/p>\n\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tNguyen, A.T.C., Le Nguyen, N.T., Hoang, T.T.A., Nguyen, T.T., Tran, T.T.Q., Tran, D.N.T., Nguyen, A.T.K., Tran, L.M., Nguyen, D.H.C., Le, T.M., Ho, B.D., R\u00f6\u00f6p, T., K\u00f5ljalg, S., \u0160t\u0161epetova, J., Van Le, A., Salumets, A. and M\u00e4ndar, R. (2022). Aerobic vaginitis in the third trimester and its impact on pregnancy outcomes. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04761-5<\/a>\n<\/p>\n\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tVargas, E., Garc\u00eda-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altm\u00e4e, S. (2022). The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis. Human Reproduction Open, 2022(2). https:\/\/doi.org\/10.1093\/hropen\/hoac016<\/a>\u00a0\n<\/p>\n\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tLavogina, D., Lust, H., Tahk, M.-J., Laasfeld, T., Vellama, H., Nasirova, N., Vardja, M., Eskla, K.-L., Salumets, A., Rinken, A. and Jaal, J. (2022). Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon.\u00a0Biosensors, 12(4), p.196. https:\/\/doi.org\/10.3390\/bios12040196<\/a>\n<\/p>\n\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tvon Grothusen, C., Frisendahl, C., Modhukur, V., Lalitkumar, P.G., Peters, M., Faridani, O.R., Salumets, A., Boggavarapu, N.R. and Gemzell-Danielsson, K. (2022). Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure. Human Reproduction, 37(4), pp.734\u2013746. https:\/\/doi.org\/10.1093\/humrep\/deac019<\/a>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tZhytnik, L., Peters, M., Tilk, K., Reimand, T., Ilisson, P., Kahre, T., Murumets, \u00dc., Ehrenberg, A., Ustav, E.-L., T\u00f5nisson, N., M\u00f6lder, S., Teder, H., Krjut\u0161kov, K. and Salumets, A. (2022). Prenatal diagnosis of a 46,XY karyotype female fetus with an SRY-associated gonadal dysgenesis, conceived through an intracytoplasmic sperm injection: a case report. BMC Pregnancy and Childbirth, 22(1). https:\/\/doi.org\/10.1186\/s12884-022-04431-6<\/a>\n<\/p>\n\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tL\u00fcll, K., Saare, M., Peters, M., Kakhiani, E., Zhdanova, A., Salumets, A., Boyarsky, K. and Org, E. (2022). Differences in microbial profile of endometrial fluid and tissue samples in women with in vitro fertilization failure are driven by Lactobacillus abundance. Acta Obstetricia et Gynecologica Scandinavica, 101(2), pp.212\u2013220. https:\/\/doi.org\/10.1111\/aogs.14297<\/a>\n<\/p>\n\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tModhukur, V., Sharma, S., Mondal, M., Lawarde, A., Kask, K., Sharma, R. and Salumets, A. (2021). Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles. Cancers, 13(15), p.3768. https:\/\/doi.org\/10.3390\/cancers13153768<\/a>\n<\/p>\n\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tPaluoja, P., Teder, H., Ardeshirdavani, A., Bayindir, B., Vermeesch, J., Salumets, A., Krjut\u0161kov, K. and Palta, P. (2021). Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples. PLOS Computational Biology, 17(12), p.e1009684. <\/span><\/span>https:\/\/doi.org\/10.1371\/journal.pcbi.1009684<\/span><\/a>\n<\/p>\n\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tNikolova, M., Naydenov, M., Glogovitis, I., Apostolov, A., Saare, M., Boggavarapu, N., Salumets, A., Baev, V. and Yahubyan, G. (2021). Coupling miR\/isomiR and mRNA Expression Signatures Unveils New Molecular Layers of Endometrial Receptivity. Life, 11(12), p.1391. https:\/\/doi.org\/10.3390\/life11121391<\/a>\n<\/p>\n\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tSim\u00f3n-Gracia, L., Kiisholts, K., Petrikait\u0117, V., Tobi, A., Saare, M., Lingasamy, P., Peters, M., Salumets, A. and Teesalu, T. (2021). Homing Peptide-Based Targeting of Tenascin-C and Fibronectin in Endometriosis. Nanomaterials, 11(12), p.3257. https:\/\/doi.org\/10.3390\/nano11123257<\/a> <\/span><\/span>\n<\/p>\n\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tRooda, I., Kaselt, B., Liivrand, M., Smolander, O.-P., Salumets, A. and Velthut-Meikas, A. (2021). Hsa-mir-548 family expression in human reproductive tissues. BMC Genomic Data, 22(1). https:\/\/doi.org\/10.1186\/s12863-021-00997-w<\/a> <\/span><\/span>\n<\/p>\n\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKiisholts, K., Kurrikoff, K., Arukuusk, P., Porosk, L., Peters, M., Salumets, A. and Langel, \u00dc. (2021). Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models. Pharmaceutics, 13(10), p.1618. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/pharmaceutics13101618<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tSchobers, G., Koeck, R., Pellaers, D., Stevens, S.J.C., Macville, M.V.E., Paulussen, A.D.C., Coonen, E., van den Wijngaard, A., de Die-Smulders, C., de Wert, G., Brunner, H.G. and Zamani Esteki, M. (2021). Liquid biopsy: state of reproductive medicine and beyond. Human Reproduction, 36(11), pp.2824\u20132839. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab206<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tKhatun, M., Meltsov, A., Lavogina, D., Loid, M., Kask, K., Arffman, R.K., Rossi, H.-R., L\u00e4ttekivi, F., J\u00e4\u00e4ger, K., Krjut\u0161kov, K., Rinken, A., Salumets, A. and Piltonen, T.T. (2021). Decidualized endometrial stromal cells present with altered androgen response in PCOS. Scientific Reports, 11(1). <\/span><\/span><\/span>https:\/\/doi.org\/10.1038\/s41598-021-95705-0<\/span><\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tZhytnik, L., Peters, M., Tilk, K., Simm, K., T\u00f5nisson, N., Reimand, T., Maasalu, K., Acharya, G., Krjut\u0161kov, K. and Salumets, A. (2021). From late fatherhood to prenatal screening of monogenic disorders: evidence and ethical concerns. Human Reproduction Update, 27(6), pp.1056\u20131085. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humupd\/dmab023<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tLavogina, D., Stepanjuk, A., Peters, M., Samuel, K., Kasvandik, S., Khatun, M., Arffman, R.K., Enkvist, E., Viht, K., Kopanchuk, S., L\u00e4ttekivi, F., Velthut-Meikas, A., Uri, A., Piltonen, T.T., Rinken, A. and Salumets, A. (2021). Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization. Human Reproduction, 36(8), pp.2230\u20132248. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.1093\/humrep\/deab161<\/span><\/a><\/span><\/span><\/span>\n<\/p>\n\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tL\u00e4\u00e4nelaid, S., Ortega, F.B., Kunovac Kallak, T., Joelsson, L., Ruiz, J.R., Hreinsson, J., W\u00e5nggren, K., Stavreus-Evers, A., Kalda, R., Salumets, A. and Altm\u00e4e, S. (2021). Physical and Sedentary Activities in Association with Reproductive Outcomes among Couples Seeking Infertility Treatment: A Prospective Cohort Study. International Journal of Environmental Research and Public Health, 18(5), p.2718. <\/span><\/span><\/span><\/span><\/span>https:\/\/doi.org\/10.3390\/ijerph18052718<\/span><\/a><\/span><\/span><\/span> <\/span><\/span>\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Press releases<\/button>\n <\/h2>\n \n \n\n\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n
\n\tViljakus esitab \u00fchiskonnale ja paaridele palju v\u00e4ljakutseid. Seminaril arutleti l\u00e4hemalt reproduktiivmeditsiini teemade \u00fcle<\/a> (Eng. Fertility poses many challenges for society and couples. The seminar took a closer look at reproductive medicine issues.), 31.10.2023, University of Tartu\n<\/p>\n\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tSeminaril v\u00f5etakse luubi alla reproduktiivmeditsiin<\/a> (Eng. Seminar focuses on reproductive medicine), 22.09.2023, University of Tartu\n<\/p>\n\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tBarlova teadus\u00f5htu \u201eLet\u2019s chill ehk viljakuse s\u00e4ilitamise sajand?\u201c<\/a> (Eng. \u201eBarlova Science Night \u201cLet\u2019s chill or the century of fertility preservation?\u201d)<\/em>, 26.05.2023,\u00a0University of Tartu\n<\/p>\n\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cUuring paljastas geenid, mis annavad lootust viljatutele paaridele<\/a>\u201c, (Eng. \u201cStudy reveals genes that give hope to infertile couples\u201d)<\/em>, 10.11.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cTartu teadlased t\u00f5stavad loote kromosoomiuuringu tipptasemele<\/a>\u201d (Eng. \u201cTartu researchers take fetal chromosome screening to the cutting edge\u201d)<\/em>, 23.09.2022, University of Tartu\n<\/p>\n\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cTartu \u00dclikooli Kliinilise meditsiini instituudi t\u00f6\u00f6 p\u00e4lvis rahvusvahelise teaduspreemia<\/a>\u201d (Eng. \u201cResearch from the Institute of Clinical Medicine of the University of Tartu wins international research award\u201d)<\/em>, 25.08.2022, University of Tartu\n<\/p>\n\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cNovel DNA analysis technology improves accuracy of prenatal screening<\/a>\u201c, 28.10.2021, University of Tartu\n<\/p>\n\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cUus DNA-anal\u00fc\u00fcsi tehnoloogia muudab loote s\u00f5eluuringu t\u00e4psemaks<\/a>\u201d (Eng. \u201cNovel DNA analysis technology improves accuracy of prenatal screening\u201d)<\/i>, 27.10.2021, University of Tartu\n<\/p>\n\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cA genetic study revealed the causes behind the side effects of infertility treatment<\/a>\u201c, 13.09.2021, University of Tartu\n<\/p>\n\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cGeeniuuringu k\u00e4igus avastati viljatusravi k\u00f5rvaltoimete p\u00f5hjused<\/a>\u201d (Eng. \u201cA genetic study revealed the causes behind the side effects of infertility treatment\u201d)<\/i>, 23.08.2021, University of Tartu\n<\/p>\n\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cSuurima toetuslepingute mahuga meditsiiniteadlaste TOP 5<\/a>\u201d (Eng. \u201eTOP5 largest grants of UT medical researchers\u201c)<\/i>, 05.02.2021, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute<\/a>\u201c, 07.12.2020, University of Tartu\n<\/p>\n\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cAndres Salumets nimetati esimese eestlasena Karolinska Instituudi professoriks<\/a>\u201d (Eng. \u201cAndres Salumets became the first Estonian to be appointed professor of Karolinska Institute\u201d)<\/i>, 26.11.2020, University of Tartu\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Public deliverables<\/button>\n <\/h2>\n \n \n\n\n\tNo public deliverables yet.\n<\/p>\n\n\t<\/p><\/div>\n <\/div>\n <\/div>\n <\/div>\n\n\n\t<\/p>\n \n \n Media<\/button>\n <\/h2>\n \n \n\n\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\tNo public deliverables yet.\n<\/p>\n
\n\t\u201cElina Aleksejeva: lapse saamise (gen)eetilised innovatsioonid<\/a>\u201d (Eng. \u201cElina Aleksejeva: (Gen)ethical innovations in childbearing\u201d<\/em>), 14.12.2023, Novaator\n<\/p>\n\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cKuni 70 protsenti rasedustest v\u00f5ib katkeda geneetilistel p\u00f5hjustel<\/a>\u201d (Eng. \u201cUp to 70 percent of pregnancies may be miscarried for genetic reasons\u201d<\/em>), 27.11.2023, Aktuaalne Kaamera\n<\/p>\n\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cKadri Simm juurdleb eetiliste otsuste \u00fcle\u201d<\/a> (Eng.\u00a0\u201cKadri Simm reflects on ethical decisions\u201d<\/em>), November 2023, Universitas Tartuensis\n<\/p>\n\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cKadri Simm ja Kairi Kreegipuu: milleks on vaja teaduseetikat?<\/a>\u201d\u00a0(Eng. \u201eKadri Simm and Kairi Kreegipuu: why do we need science ethics?\u201c)<\/em>, 15.08.2023 ERR\n<\/p>\n\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201cP\u00f5hjalikumad kromosoomhaiguste uuringud v\u00e4listaks tuvastamata kromosoomhaigusega laste s\u00fcnni. Miks neid k\u00f5igile rasedatele ei pakuta?<\/a>\u201d\u00a0(Eng. \u201cMore comprehensive chromosome disease testing would rule out the birth of children with an undetected chromosome disease. Why are they not offered to all pregnant women?\u201d)<\/em>, 09.08.2023, Pere & Kodu\n<\/p>\n\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c
\n\t\u201c\u0422\u0430\u0440\u0442\u0443\u0441\u043a\u0438\u0435 \u0443\u0447\u0435\u043d\u044b\u0435 \u0443\u0441\u043e\u0432\u0435\u0440\u0448\u0435\u043d\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 \u043c\u0435\u0442\u043e\u0434 \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0445\u0440\u043e\u043c\u043e\u0441\u043e\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a>\u201c