{"id":8,"date":"2024-04-04T04:47:00","date_gmt":"2024-04-04T01:47:00","guid":{"rendered":"https:\/\/sisu.ut.ee\/cgem\/research-fields\/"},"modified":"2024-05-06T08:06:34","modified_gmt":"2024-05-06T05:06:34","slug":"research-fields","status":"publish","type":"page","link":"https:\/\/sisu.ut.ee\/cgem\/research-fields\/","title":{"rendered":"Research fields"},"content":{"rendered":"

evolutionarily-aware medicine<\/strong> \u2013 Since numerous gene variants contribute to the differences in human conditions including diseases, the understanding of genetic variation beyond registering the differences and their disease associations is crucial for revealing the etiology of the diseases. It is through evolution \u2013 the process of change to the genetic diversity patterns brought upon by interaction with the environment, i.e. natural selection and random genetic drift, effects of which are manifested through differential demographic histories of human populations \u2013 that we have arrived where we are today, where some genetic variants make you predisposed to become sick, some protect you and most have probably no notable role.<\/p>\n\n\n\n

Here are some research directions that we envisage to profit the
most from the proliferation of synergy in the cGEM project:\u00a0<\/h3>\n\n\n\n

\"Image
Global and molecular pathway-based changes in mutation rate and type<\/p>\n\n\n\n

\"Image
Differences in demographic history and regional selection pressures shape predisposition to disease<\/p>\n\n\n\n

\"Image
Population genomics-based personalised medicine<\/p>\n\n\n\n

\"Image
Pharmacogenomics<\/p>\n\n\n\n

\"Image
Personalised medicine in cancer management of admixed populations<\/p>\n\n\n\n

\"Image
Minimally invasive screening for early cancer diagnostics<\/p>\n\n\n\n

\"Image
Minimally invasive screening methods in personalized cancer management<\/p>\n\n\n\n

\"Image
Progress of liquid biopsy technologies<\/p>\n","protected":false},"excerpt":{"rendered":"

evolutionarily-aware medicine \u2013 Since numerous gene variants contribute to the differences in human conditions including diseases, the understanding of genetic variation beyond registering the differences and their disease associations is crucial for revealing the etiology of the diseases. It is …<\/p>\n","protected":false},"author":154,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/pages\/8","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/users\/154"}],"replies":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/comments?post=8"}],"version-history":[{"count":12,"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/pages\/8\/revisions"}],"predecessor-version":[{"id":390,"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/pages\/8\/revisions\/390"}],"wp:attachment":[{"href":"https:\/\/sisu.ut.ee\/cgem\/wp-json\/wp\/v2\/media?parent=8"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}