{"id":29,"date":"2024-04-04T03:13:00","date_gmt":"2024-04-04T00:13:00","guid":{"rendered":"https:\/\/sisu.ut.ee\/cemce\/c1\/"},"modified":"2024-04-04T03:15:01","modified_gmt":"2024-04-04T00:15:01","slug":"c1","status":"publish","type":"page","link":"https:\/\/sisu.ut.ee\/cemce\/c1\/","title":{"rendered":"C1."},"content":{"rendered":"<div class=\"page\" title=\"Page 8\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p><span>C1. Modulators of viral replication <\/span><\/p>\n<p><span>Specific chemicals targeting viral replication and maintenance mechanisms will be developed (design by group 1; synthesis by Group 6; biological tests by Group 5 and assistance for delivery from Group 7). The viruses in focus are papillomaviruses, alphaviruses and retroviruses. These viruses are being used by Group 5 for developing new vector systems for protein expression and gene therapy (<\/span><span>6<\/span><span>, <\/span><span>7<\/span><span>). The specific chemicals promise tighter and more flexible control of the systems. In addition, the chemical probes can serve as leads for the development of antiviral compounds, as a means to modulate virus infection <\/span><span>in vivo <\/span><span>and serve as very useful tools for studies of viral replication cycles.\u00a0<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>C1. Modulators of viral replication Specific chemicals targeting viral replication and maintenance mechanisms will be developed (design by group 1; synthesis by Group 6; biological tests by Group 5 and assistance for delivery from Group 7). The viruses in focus &#8230;<\/p>\n","protected":false},"author":39,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-29","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/pages\/29","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/users\/39"}],"replies":[{"embeddable":true,"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/comments?post=29"}],"version-history":[{"count":1,"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/pages\/29\/revisions"}],"predecessor-version":[{"id":392,"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/pages\/29\/revisions\/392"}],"wp:attachment":[{"href":"https:\/\/sisu.ut.ee\/cemce\/wp-json\/wp\/v2\/media?parent=29"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}